There will be no more lighting up in bars and casinos as of midnight.
After being excluded from the Clean Indoor Act for four years, time has run out for businesses that attract the most smokers.
In Butte, preparations for the big change are noticeable around town with smoking shacks going up, including at Lisac's Tri-Stop and Good Tymes Casino on Harrison Avenue.
Owner Elaine Lisac says she remains positive about the change despite some worries.
"My biggest concern is that we're going to see a drop in business. They're telling me 25 percent of people in Butte smoke, and I always thought that was higher, so I'm hoping. I know we'll see a drop, maybe for a couple of weeks, but I'm hoping we'll build back up and even be stronger than before," Lisac said.
Lisac also says most of her employees smoke, but many have decided to quite starting Thursday.
Prevention Specialist Ben Pezdark of the Health Department said policing the Clean Indoor Act will be mostly community driven.
"We don't look forward to seeing a lot of problems with this. We're giving people a little bit of leeway, a lot of information and education will go out before any fines are levied on anybody," Pezdark said.
Once the state notifies the health department of a complaint, officials will go and investigate, according to Pezdark.
Fines run from $100 to $500.